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Optimizing assessmentand treatment forhepatitis C virusinfection in illicitdrug users: a novelmodel incorporatingmultidisciplinarycare and peer support Jason GrebelyElizabeth KnightKrista Genoway2010 год

Optimizing assessment and treatment for hepatitis C virus infection in illicit drug users: a novel model incorporating multidisciplinary care and peer support
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Аннотация: We evaluated assessment and treatment for hepatitis C virus (HCV) among illicit drug users accepting referral to a weekly HCV peer-support group at a multidisciplinary community health centre.From March 2005 to 2008, HCV-infected individuals were referred to a weekly peer-support group and assessed for HCV infection. A retrospective chart review of outcomes 3 years after the initiation of the group was conducted (including HCV assessment and treatment).Two hundred and four HCV antibody-positive illicit drug users accepted referral to a weekly HCV peer-support group. Assessment for HCV occurred in 53% of patients(n= 109), with 13% (n= 14) having initiated or completed treatment for HCV infection before attending the support group, evaluation ongoing in 10% (n= 11) and treatment deferred/not indicated in 25% (n= 27). The major reasons for HCV treatment deferral included early disease (30%),drug dependence (37%), other medical (11%) or psychiatric comorbidities (4%). Sixty-eight percent of those deferred for reasons other than early liver disease showed multiple reasons for treatment deferral. The first 4 weeks of support group attendance predicted successful HCV assessment (odds ratio: 6.03, 95% confidence interval:3.27-11.12, P < 0.001). Overall, 28% (n= 57) received treatment. Among individuals having completed pegylated-interferon and ribavirin therapy with appropriate follow-up (n =19), the rate of sustained virologic response was 63% (12/19), despite illicit drug use in 53%.A high proportion of illicit drug users accepting referral to a weekly HCV peer-support group at a multidisciplinary health centre were assessed and treated for HCV infection. Peer support coupled with multidisciplinary care is an effective strategy for engaging illicit drug users in HCV care.
Год издания: 2010
Авторы: Jason Grebely, Elizabeth Knight, Krista Genoway, Mark Viljoen, Milan Khara, Doug Elliott, Lesley Gallagher, Michelle Storms, Jesse D. Raffa, Stanley DeVlaming, Fiona Duncan, Brian Conway
Издательство: Lippincott Williams & Wilkins
Источник: European Journal of Gastroenterology & Hepatology
Ключевые слова: Hepatitis C virus research, Liver Disease Diagnosis and Treatment, Hepatitis B Virus Studies
Другие ссылки: European Journal of Gastroenterology & Hepatology (HTML)
cIRcle (University of British Columbia) (PDF)
cIRcle (University of British Columbia) (HTML)
PubMed (HTML)