The effect of myocardial fibrosis on ventricular remodeling following valve replacement for severe aortic stenosis. A CMR study comparing transcatheter aortic valve implantation and surgical aortic valve replacement
Аннотация:Myocardial fibrosis (MF) that occurs in aortic stenosis (AS) has been shown to be associated with a poor prognostic outcome post surgical aortic valve replacement (SAVR) but not in the high risk patients suitable for Transcatheter aortic valve implantation (TAVI).Using the technique of late-gadolinium enhancement we have shown that MF regresses post-TAVI but not post-SAVR, and that ejection fraction rather than MF is the independent predictor of reverse remodeling.