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A Case of AutoimmunePancreatitisDeveloped PancreaticTail Cancer Hiroshi IidaKensuke KubotaMasato Yoneda2009 год

A Case of Autoimmune Pancreatitis Developed Pancreatic Tail Cancer
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Аннотация: A-59-year-old man was readmitted to our hospital because of jaundice for two years interval. Endoscopic retrograde pancreatography (ERP) showed diffuse narrowing in the main pancreatic duct and CT revealed focal swelling in the head of the pancreas. Serum IgG4 was 334 mg/dl. A diagnosis of relapse of Autoimmune pancreatitis (AIP) was made. After initiating corticosteroid therapy for six months, pancreatic tail cancer with multiple liver and bone metastasis was depicted on PET/CT with raise of CA19-9 364U/ml. Although systemic chemotherapy was performed, the result showed progressive diseases. AIP originally described by Sarles et al in 1961 as "primary inflammatory sclerosis of the pancreas",1 the term AIP was introduced by Yoshida et al in 1995.2 AIP has been regarded as a clinically characterized by response to steroid therapy and a favorable prognosis,3 besides, AIP cases could potentially develop pancreatic cancer. Recently, AIP with pancreatic cancer has been reported (Table 1). The natural history of AIP after corticosteroid therapy, such as the frequency and nature of relapse, carcinogenesis, etc. has not yet been clarified. The pancreatic cancer was diagnosed 5 years 4 months after the AIP had been diagnosed in our case, therefore, we have to bare in mind that AIP may predispose to pancreatic cancer. Close followed up examinations are mandatory for AIP cases even after the remission.TABLE 1: Cases of pancreatic carcinoma with AIP (n = 12)
Год издания: 2009
Авторы: Hiroshi Iida, Kensuke Kubota, Masato Yoneda, Ayumu Goto, Yasunobu Abe, Masahiko Inamori, Hiroyuki Kirikoshi, Satoru Saito, Atsushi Nakajima
Издательство: Lippincott Williams & Wilkins
Источник: Pancreas
Ключевые слова: IgG4-Related and Inflammatory Diseases, Gastrointestinal disorders and treatments, Neuroendocrine Tumor Research Advances
Другие ссылки: Pancreas (HTML)
journals.lww.com (HTML)