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Medicinal plants inthe treatmentofHelicobacterpyloriinfections Maliheh SafaviMohammadreza Shams‐ArdakaniAlireza Foroumadi2014 год

Medicinal plants in the treatment ofHelicobacter pyloriinfections
review

Страница публикацииПубликация в OpenAlex
Аннотация: Context: Helicobacter pylori is a small, spiral, Gram-negative bacillus that plays a role in the pathogenesis of a number of diseases ranging from asymptomatic gastritis to gastric cancer. Schedule compliance, antibiotic drug resistance, and side-effects of triple or quadruple therapy have led to research for novel candidates from plants.Objective: The purpose of this paper is to review the most potent medicinal plants of recently published literature with anti-H. pylori activity. For centuries, herbals have been used by traditional healers around the world to treat various gastrointestinal tract disorders such as dyspepsia, gastritis, and peptic ulcer disease. The mechanism of action by which these botanicals exert their therapeutic properties has not been completely and clearly elucidated. Anti-H. pylori properties may be one of the possible mechanisms by which gastroprotective herbs treat gastrointestinal tract disorders.Materials and methods: Electronic databases such as PubMed, Google scholar, EBSCO, and local databases were explored for medicinal plants with anti-H. pylori properties between 1984 and 2013 using key words "medicinal plants" and "Helicobacter pylori" or "anti-Helicobacter pylori".Results: A total of 43 medicinal plant species belonging to 27 families including Amaryllidaceae, Anacardiaceae, Apiaceae, Apocynaceae, Asclepiadoideae, Asteraceae, Bignoniaceae, Clusiaceae, Chancapiedra, Combretaceae, Cyperaceae, Euphorbiaceae, Fabaceae, Geraniaceae, Lamiaceae, Lauraceae, Lythraceae, Menispermaceae, Myristicaceae, Myrtaceae, Oleaceae, Papaveraceae, Plumbaginaceae, Poaceae, Ranunculaceae, Rosaceae, and Theaceae were studied as herbs with potent anti-H. pylori effects.Conclusion: Traditional folk medicinal use of some of these plants to treat gastric infections is substantiated by the antibacterial activity of their extracts against H. pylori.
Год издания: 2014
Авторы: Maliheh Safavi, Mohammadreza Shams‐Ardakani, Alireza Foroumadi
Издательство: Taylor & Francis
Источник: Pharmaceutical Biology
Ключевые слова: Helicobacter pylori-related gastroenterology studies, Phytochemistry and Bioactive Compounds, Phytochemistry and biological activities of Ficus species
Другие ссылки: Pharmaceutical Biology (HTML)
PubMed (HTML)