Аннотация:C. elegans has a highly developed chemosensory system that enables it to detect a wide variety of volatile (olfactory) and water-soluble (gustatory) cues associated with food, danger, or other animals.Much of its nervous system and more than 5% of its genes are devoted to the recognition of environmental chemicals.Chemosensory cues can elicit chemotaxis, rapid avoidance, changes in overall motility, and entry into and exit from the alternative dauer developmental stage.These behaviors are regulated primarily by the amphid chemosensory organs, which contain eleven pairs of chemosensory neurons.Each amphid sensory neuron expresses a specific set of candidate receptor genes and detects a characteristic set of attractants, repellents, or pheromones.About 500-1000 different G protein-coupled receptors (GPCRs) are expressed in Chemosensory neurons generally belong to bilaterally symmetric pairs in which the left and right members of each class are structurally similar.Each left-right pair forms a class that can be distinguished from all other classes based on cilium morphology, axon morphology, and synaptic targets (White et al., 1986).Both anatomy and Chemosensation in C. elegans
