Аннотация:infections because of multiple drug resistance and alternate survival strate-gies like biofilm formation. Side effects due to toxicity is another problem associated with these drugs. Hence, there is a need to search for novel molecules with antifungal activities (Mishra et al. 2007; Oncu, 2011). Designing a new drug is a time- and money-consuming process. Drug repurposing/repositioning, which in-volves revealing novel bioactivities of drugs already being used in therapeutics (for treatment of a different ailment), is an attractive strategy (Ashburn and Thor, 2004). For example, cisplatin, which was originally dis -covered as an antimicrobial, proved to be an effective tumor inhibitor. Azole antifungals were shown to have good anti-mycobacterium activities, while anticancer agents were reported to possess potential anti-
Источник:The Journal of General and Applied Microbiology
Ключевые слова:Antifungal resistance and susceptibility, Cancer therapeutics and mechanisms, Phenothiazines and Benzothiazines Synthesis and Activities
