1. Главная
  2. Ресурсы
  3. Библиотечный поиск
EnvironmentalEnrichment ImprovesResponse Strength,Threshold,Selectivity, andLatency of AuditoryCortex Neurons Navzer D. EngineerCherie R. PercaccioPritesh K. Pandya2004 год

Environmental Enrichment Improves Response Strength, Threshold, Selectivity, and Latency of Auditory Cortex Neurons
статья из журнала

Полный текстСтраница публикацииПубликация в OpenAlex
Аннотация: Over the last 50 yr, environmental enrichment has been shown to generate more than a dozen changes in brain anatomy. The consequences of these physical changes on information processing have not been well studied. In this study, rats were housed in enriched or standard conditions either prior to or after reaching sexual maturity. Evoked potentials from awake rats and extracellular recordings from anesthetized rats were used to document responses of auditory cortex neurons. This report details several significant, new findings about the influence of housing conditions on the responses of rat auditory cortex neurons. First, enrichment dramatically increases the strength of auditory cortex responses. Tone-evoked potentials of enriched rats, for example, were more than twice the amplitude of rats raised in standard laboratory conditions. Second, cortical responses of both young and adult animals benefit from exposure to an enriched environment and are degraded by exposure to an impoverished environment. Third, housing condition resulted in rapid remodeling of cortical responses in <2 wk. Fourth, recordings made under anesthesia indicate that enrichment increases the number of neurons activated by any sound. This finding shows that the evoked potential plasticity documented in awake rats was not due to differences in behavioral state. Finally, enrichment made primary auditory cortex (A1) neurons more sensitive to quiet sounds, more selective for tone frequency, and altered their response latencies. These experiments provide the first evidence of physiologic changes in auditory cortex processing resulting from generalized environmental enrichment.
Год издания: 2004
Авторы: Navzer D. Engineer, Cherie R. Percaccio, Pritesh K. Pandya, Raluca Moucha, Daniel L. Rathbun, Michael P. Kilgard
Издательство: American Physiological Society
Источник: Journal of Neurophysiology
Ключевые слова: Neural dynamics and brain function, Neuroscience and Neuropharmacology Research, Neuroendocrine regulation and behavior
Другие ссылки: Journal of Neurophysiology (HTML)
CiteSeer X (The Pennsylvania State University) (PDF)
CiteSeer X (The Pennsylvania State University) (HTML)
PubMed (HTML)