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Applications of goldnanoparticles incancer nanotechnology Weibo Cai2008 год

Applications of gold nanoparticles in cancer nanotechnology
review

Полный текстСтраница публикацииПубликация в OpenAlex
Аннотация: Abstract: It has been almost 4 decades since the "war on cancer" was declared. It is now generally believed that personalized medicine is the future for cancer patient management. Possessing unprecedented potential for early detection, accurate diagnosis, and personalized treatment of cancer, nanoparticles have been extensively studied over the last decade. In this review, we will summarize the current state-of-the-art of gold nanoparticles in biomedical applications targeting cancer. Gold nanospheres, nanorods, nanoshells, nanocages, and surface enhanced Raman scattering nanoparticles will be discussed in detail regarding their uses in in vitro assays, ex vivo and in vivo imaging, cancer therapy, and drug delivery. Multifunctionality is the key feature of nanoparticle-based agents. Targeting ligands, imaging labels, therapeutic drugs, and other functionalities can all be integrated to allow for targeted molecular imaging and molecular therapy of cancer. Big strides have been made and many proof-of-principle studies have been successfully performed. The future looks brighter than ever yet many hurdles remain to be conquered. A multifunctional platform based on gold nanoparticles, with multiple receptor targeting, multimodality imaging, and multiple therapeutic entities, holds the promise for a "magic gold bullet" against cancer. Keywords: gold nanoparticles, cancer, nanotechnology, optical imaging, nanomedicine, molecular therapy
Год издания: 2008
Авторы: Weibo Cai
Издательство: Dove Medical Press
Источник: Nanotechnology Science and Applications
Ключевые слова: Gold and Silver Nanoparticles Synthesis and Applications, Nanoparticle-Based Drug Delivery, Advanced biosensing and bioanalysis techniques
Другие ссылки: Nanotechnology Science and Applications (PDF)
Nanotechnology Science and Applications (HTML)
DOAJ (DOAJ: Directory of Open Access Journals) (HTML)
PubMed Central (HTML)
Europe PMC (PubMed Central) (PDF)
Europe PMC (PubMed Central) (HTML)
PubMed (HTML)