Assessment of Biomedical Risk Factors Associated with Adverse Pregnancy Outcomes : научное издание

Lukyanova N.; Melnikova O.

Дополнительные ссылки: eLibrary

База данных: Каталог библиотеки СФУ

Библиографическое описание: Assessment of Biomedical Risk Factors Associated with Adverse Pregnancy Outcomes : научное издание / N. Lukyanova, O. Melnikova. - Текст : непосредственный // Advances in Intelligent Systems and Computing (см. в книгах). - 2020. - Т. 1294, № . - P. 883-893. - ISSN 2194-5357, DOI 10.1007/978-3-030-63322-6_75.

Аннотация: Purpose of research is determine the risk factors for premature birth using the data of perinatal monitoring of the Krasnoyarsk territory. Methods: retrospective case-control study of 118412 pregnant women. The analyzed data set is described by a binary context - a matrix, the rows of which correspond to units of observation as a case of pregnancy with a favorable and an adverse outcome, and the columns - to the biomedical risk factors for each cases. Researched by 54 risk factors on obstetric and gynecological medical history and somatic diseases of the mother. The multi-calculater of odds ratio has been developed which can calculating an odds ratios simultaneously for all risk factors from dataset, with the help of which the influence of biomedical factors on the risk of premature birth is analyzed. The calculations are implemented by a programming language R. According to the studied statistical material, 31 factors were established that increase the chances of detecting a risk factor in the group “Preterm birth”, the revealed relationship of factors with outcome is statistically significant at p< 0.05. To the greatest extent, this risk is influenced by the presence of a positive reaction to lupus anticoagulant, diabetes mellitus, hypertension of II and III severity in the mother.

Год издания: 2020

Авторы: Lukyanova N. , Melnikova O.

Источник: Advances in Intelligent Systems and Computing (см. в книгах)

Выпуск: Т. 1294

Номера страниц: 883-893

Держатель оригинала документа: Institute of Mathematics and Computer Science of Siberian Federal University, Reshetnev Siberian State University of Science and Technology, Voino-Yasenetsky Krasnoyarsk State Medical University

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