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The metabolic changesin tumor-associatedmacrophages duringcancer grow in micewith Ehrlich ascitescarcinoma Inzhevatkin E.V.Savchenko A.A.2017 год

The metabolic changes in tumor-associated macrophages during cancer grow in mice with Ehrlich ascites carcinoma : научное издание
статья из журнала

Дополнительные ссылки: РИНЦ
База данных: Каталог библиотеки СФУ
Библиографическое описание: The metabolic changes in tumor-associated macrophages during cancer grow in mice with Ehrlich ascites carcinoma : научное издание / E. V. Inzhevatkin, A. A. Savchenko. - Текст : непосредственный // Doklady Biochemistry and Biophysics. - 2017. - Т. 475, № 1. - P. 277-279. - ISSN 1607-6729. - ISSN 1608-3091, DOI 10.1134/S1607672917040081.
Аннотация: In this work, we investigated the activity of the key NAD(P)-dependent dehydrogenases associated with macrophage tumors in mice with Ehrlich ascites carcinoma. It was shown that cancer grow is associated with the development of conditions in macrophages leading to a decrease in the substrate flow intensity in the tricarboxylic acid cycle, deceleration of oxidative deamination of L-glutamate, NADP regeneration, and a decrease in the antioxidant defense efficiency. There results are consistent with our recent concept on the nonspecific metabolic reaction of cells to extreme exposures.
Год издания: 2017
Авторы: Inzhevatkin E.V. , Savchenko A.A.
Издательство: Pleiades Publishing, Ltd. (Плеадес Паблишинг, Лтд), Москва
Источник: Doklady Biochemistry and Biophysics
Выпуск: Т. 475, № 1
Номера страниц: 277-279
Держатель оригинала документа: Federal Research Center Krasnoyarsk Scientific Center of the Siberian Branch of the RAS, Research Institute for Medical Problems in the North Division of Federal Research Center “Krasnoyarsk Scientific Center of the Siberian Branch of the RAS”
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