Human epithelial cells trigger dendritic cell–mediated allergic inflammation by producing TSLP
Whether epithelial cells play a role in triggering the immune cascade leading to T helper 2 (T
H 2)-type allergic inflammation is not known. We show here that human thymic stromal …
H 2)-type allergic inflammation is not known. We show here that human thymic stromal …
Immunobiology of dendritic cells
…, C Caux, J Davoust, S Lebecque, YJ Liu… - Annual review of …, 2000 - annualreviews.org
Dendritic cells (DCs) are antigen-presenting cells with a unique ability to induce primary
immune responses. DCs capture and transfer information from the outside world to the cells of …
immune responses. DCs capture and transfer information from the outside world to the cells of …
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
…, M Liu, D Gorman, J Wagner, S Zurawski, YJ Liu… - Immunity, 2000 - cell.com
A novel sequence discovered in a computational screen appears distantly related to the p35
subunit of IL-12. This factor, which we term p19, shows no biological activity by itself; instead…
subunit of IL-12. This factor, which we term p19, shows no biological activity by itself; instead…
[HTML][HTML] Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity
YJ Liu - Cell, 2001 - cell.com
Dendritic cells (DCs) are professional antigen presenting cells, which display an extraordinary
capacity to stimulate naı̈ve T cells and initiate primary immune responses. This …
capacity to stimulate naı̈ve T cells and initiate primary immune responses. This …
Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus
Hassall's corpuscles—first described in the human thymus over 150 years ago 1 —are groups
of epithelial cells within the thymic medulla. The physical nature of these structures differs …
of epithelial cells within the thymic medulla. The physical nature of these structures differs …
Reciprocal control of T helper cell and dendritic cell differentiation
…, N Kadowaki, G Grouard, F Briere, RW Malefyt, YJ Liu - Science, 1999 - science.org
It is not known whether subsets of dendritic cells provide different cytokine microenvironments
that determine the differentiation of either type-1 T helper (T H 1) or T H 2 cells. Human …
that determine the differentiation of either type-1 T helper (T H 1) or T H 2 cells. Human …
Mouse and human dendritic cell subtypes
K Shortman, YJ Liu - Nature Reviews Immunology, 2002 - nature.com
Dendritic cells (DCs) collect and process antigens for presentation to T cells, but there are
many variations on this basic theme. DCs differ in the regulatory signals they transmit, …
many variations on this basic theme. DCs differ in the regulatory signals they transmit, …
IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors
YJ Liu - Annu. Rev. Immunol., 2005 - annualreviews.org
▪ Abstract Type 1 interferon-(α, β, ω)-producing cells (IPCs), also known as plasmacytoid
dendritic cell precursors (pDCs), represent 0.2%–0.8% of peripheral blood mononuclear cells in …
dendritic cell precursors (pDCs), represent 0.2%–0.8% of peripheral blood mononuclear cells in …
The nature of the principal type 1 interferon-producing cells in human blood
Interferons (IFNs) are the most important cytokines in antiviral immune responses. “Natural
IFN-producing cells” (IPCs) in human blood express CD4 and major histocompatibility …
IFN-producing cells” (IPCs) in human blood express CD4 and major histocompatibility …
Thymic stromal lymphopoietin: master switch for allergic inflammation
YJ Liu - The Journal of experimental medicine, 2006 - rupress.org
Thymic stromal lymphopoietin (TSLP) is an interleukin (IL) 7–like cytokine that triggers
dendritic cell–mediated T helper (Th)2 inflammatory responses. TSLP is highly expressed by …
dendritic cell–mediated T helper (Th)2 inflammatory responses. TSLP is highly expressed by …