Background Evidence supports an independent association between plasma total
homocysteine concentrations and the risk of vascular disease. Recent epidemiologic studies …

Background Hemoglobin concentrations slightly below the lower limit of normal are a common
laboratory finding in the elderly, but scant evidence is available on the actual occurrence …

As people age they become increasingly susceptible to chronic and extremely debilitating
brain diseases. The precise cause of the neuronal degeneration underlying these disorders, …

Background Creutzfeldt-Jakob disease (CJD) is a fatal, untreatable prion encephalopathy.
Previous studies showed that doxycycline is effective in in-vitro and in-vivo models of disease, …

Background Drugs with anticholinergic effects are associated with adverse events such as
delirium and falls as well as cognitive decline and loss of independence. Objective The aim of …

Background In the elderly persons, hemoglobin concentrations slightly below the lower limit
of normal are common, but scant evidence is available on their relationship with significant …

Background Mild anemia is a frequent laboratory finding in the elderly usually disregarded
in everyday practice as an innocent bystander. The aim of the present population-based …

Background This study reports the findings of the first large-scale Phase III investigator-driven
clinical trial to slow the rate of cognitive decline in Alzheimer disease with a …

Falls are common events in the elderly and represent the main risk factor for fractures and
other injuries. Strategies for fall prevention rely on the multifactorial assessment of the risk of …

Objective To investigate the prescribing patterns and the prevalence of polypharmacy in
community‐dwelling elderly people, and to analyze the association of chronic medications and …