Background Physical activity may help maintain cognitive function and decrease dementia
risk, but epidemiological findings remain controversial. The aim of our study was to …

Background : In adults, high blood pressure (BP), adverse serum lipids, and smoking associate
with cognitive deficits. The effects of these risk factors from childhood on midlife cognitive …

General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …

Background Leisure‐time physical activity has been related with a reduced risk of dementia
and Alzheimer's disease (AD). The effects of occupational and commuting physical activity (…

The risk of dementia and Alzheimer's disease (AD) probably results from an interaction
between genetic and environmental factors. The aim of this study was to investigate the effects …

Objectives To evaluate whether mid-life marital status is related to cognitive function in later
life. Design Prospective population based study with an average follow-up of 21 years. …

Physical activity has been associated with decreased dementia risk in recent studies, but
the effects for structural brain changes (ie white matter lesions (WMLs) and/or brain atrophy) …

Determining lifelong physical activity (PA) trajectories and their determinants is essential to
promote a physically active lifestyle throughout the life‐course. We aimed to identify PA …

Hyperlipidaemia is a major risk factor of atherosclerotic cardiovascular disease (ASCVD).
Risk of cardiovascular events depends on cumulative lifetime exposure to low-density …

Background Neighbourhood socioeconomic disadvantage has been linked to increased
diabetes risk, but little is known about differences in risk factors in childhood and adulthood in …