HIV vaccine design: insights from live attenuated SIV vaccines

…, AB McDermott, A Schultz, TJ Zamb, R Boyle… - Nature …, 2006 - nature.com
The International AIDS Vaccine Initiative has established a consortium to elucidate mechanisms
of protection conferred by live attenuated simian immunodeficiency virus vaccines in …

Macaques vaccinated with live-attenuated SIV control replication of heterologous virus

…, NA Wilson, AB McDermott, R Boyle… - Journal of Experimental …, 2008 - rupress.org
An effective AIDS vaccine will need to protect against globally diverse isolates of HIV. To
address this issue in macaques, we administered a live-attenuated simian immunodeficiency …

Macaques vaccinated with simian immunodeficiency virus SIVmac239Δnef delay acquisition and control replication after repeated low-dose heterologous SIV …

…, R Makowsky, AB McDermott, R Boyle… - Journal of …, 2010 - journals.asm.org
An effective human immunodeficiency virus (HIV) vaccine will likely need to reduce mucosal
transmission and, if infection occurs, control virus replication. To determine whether our best …

Postexposure immunoprophylaxis of primary isolates by an antibody to HIV receptor complex

…, MT Salas, M Shen, MC Gauduin, RW Boyle… - Proceedings of the …, 1999 - pnas.org
mAb B4 is a monoclonal antibody directed against HIV receptor complex. The antibody had
broad neutralizing activity against HIV and provided postexposure prophylaxis to hu–…

Phase 1 safety and immunogenicity evaluation of ADMVA, a multigenic, modified vaccinia Ankara-HIV-1 B'/C candidate vaccine

…, S Than, P Adesanya, C Bunce, M Boaz, R Boyle… - PLoS …, 2010 - journals.plos.org
Background We conducted a Phase I dose-escalation trial of ADMVA, a Clade-B'/C-based
HIV-1 candidate vaccine expressing env, gag, pol, nef, and tat in a modified vaccinia Ankara …

Phase 1 safety and immunogenicity evaluation of ADVAX, a multigenic, DNA-based clade C/B'HIV-1 candidate vaccine

…, S Than, P Adesanya, C Bunce, M Boaz, R Boyle… - PLoS …, 2010 - journals.plos.org
Background We conducted a Phase I dose escalation trial of ADVAX, a DNA-based candidate
HIV-1 vaccine expressing Clade C/B' env, gag, pol, nef, and tat genes. Sequences were …

Synthetic-peptide-based enzyme-linked immunosorbent assay for screening human serum or plasma for antibodies to human immunodeficiency virus type 1 and type …

L Gonzalez, RW Boyle, M Zhang… - Clinical Diagnostic …, 1997 - journals.asm.org
A synthetic-peptide-based enzyme-linked immunosorbent assay (EIA) capable of screening
for antibodies to both human immunodeficiency virus type 1 (HIV-1) and HIV-2 has been …

Diagnosis of chronic hepatitis C: comparison of immunoassays and the polymerase chain reaction.

AE Silva, B Hosein, RW Boyle… - American Journal of …, 1994 - search.ebscohost.com
We evaluated a series of first-and second-generation enzyme-linked immunoassays for anti-HCV
and compared the findings to those with two confirmatory assays, the recombinant …

Will the real body please stand up?: Boundary stories about virtual cultures

SA Rosanne - Cyberspace: first steps, 1991 - degruyter.com
… the debate between Boyle and the philosopher Thomas Hobbes, Leviathan and the Air-Pump,
we probably owe the invention of the boring academic paper to Boyle. Boyle developed a …

[CITATION][C] Cardiac safety/events in clinical trials with preventive HIV vaccine candidates based on Modified vaccinia Ankara (MVA)

…, D Ho, M Keefer, VD Ramanathan, B Rosanne… - 2008 - erepository.uonbi.ac.ke
Rosanne, Boyle … Schmidt C, Kochhar S, Excler JL, Smith C, McMichael A, Bwayo J,
Jaoko WG, Weber J, Kaleebu P, Peters B, Pantaleo G, Vardas E, Robinson A, Ho D, Keefer …