Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system.
…, M Haraguchi, N Takeda, K Fujimura, M Sakae… - Proceedings of the …, 1996 - pnas.org
Gangliosides, sialic acid-containing glycosphingolipids, are abundant in the vertebrate (mammalian)
nervous system. Their composition is spatially and developmentally regulated, and …
nervous system. Their composition is spatially and developmentally regulated, and …
Age-related changes in basal dendrite and dendritic spine of hippocampal pyramidal neurons (CA1) among SAMP1TANgs—quantitative analysis by the rapid Golgi …
S Kawaguchi, M Kishikawa, M Sakae… - Mechanisms of ageing …, 1995 - Elsevier
It has been confirmed that a substrain of the senescence-accelerated mouse SAMP1TA Ngs
develops learning disturbance-like behavior at 3 months of age, exhibits almost normal …
develops learning disturbance-like behavior at 3 months of age, exhibits almost normal …
Early diagnosis of Alzheimer's?
M Kishikawa, M Iseki, M Sakae, S Kawaguchi, H Fujii - 1994 - psycnet.apa.org
Comments on the observation by BR Talamo et al (see record 1989-33653-001) that biopsy
of the olfactory mucosa can be used in the early diagnosis of Alzheimer's disease (AD). An …
of the olfactory mucosa can be used in the early diagnosis of Alzheimer's disease (AD). An …
Quantitative age-related changes in apical dendrites and dendritic spines of CA1 pyramidal neurons among senescence accelerated mice (SAMP1TANgs)
I Wasowicz, M Kishikawa, M Sakae… - Mechanisms of ageing …, 1996 - Elsevier
SAMP1TA Ngs , a substrain of senescence accelerated mouse, is a useful animal model for
research on brain dysfunction due to senescence. In a previous study it was reported that …
research on brain dysfunction due to senescence. In a previous study it was reported that …
Herbal medicine and the study of aging in senescence-accelerated mice (SAMP1TA/Ngs)
M Kishikawa, M Sakae - Experimental gerontology, 1997 - Elsevier
Two types of herbal medicine, Toki-Shakuyaku-San (TSS) and Boui-Jiou-Tou (BJT), were
considered from the view point of their possible preventive effect on senility using the …
considered from the view point of their possible preventive effect on senility using the …
The learning ability and motility of senescence accelerated mice (SAM‐P/1) treated with Toki‐Shakuyaku‐San
M Kishikawa, M Nishimura, M Sakae… - Phytotherapy …, 1993 - Wiley Online Library
The effects of the Kampo medicine Toki‐Shakuyaku‐San on the motility and learning ability
of mice were studied. An assay on mice aged 5 months after 15 weeks of administration …
of mice were studied. An assay on mice aged 5 months after 15 weeks of administration …
THE EFFECT OF HERBAL PRODUCTS ON LEARNING DISTURBANCE IN SENESCENCE ACCELERATED MOUSE
M KISHIKAWA, M SAKAE, H SATO - Indian Journal of …, 1997 - journals.lww.com
The preventive effect of the Japanese herbal medicine “Boui-Jiou-Tou (BJT)” on senility
using Senescence Accelerated Mouse (SAMP 1 TA/Ngs), which is considered to be useful …
using Senescence Accelerated Mouse (SAMP 1 TA/Ngs), which is considered to be useful …
[CITATION][C] Effects of low dose of X-ray on the ConA response of mouse splenic lymphocyte
…, Y Okumura, T Shimasaki, M Kishikawa, M Sakae… - Hiroshima Igaku, 1996 - inis.iaea.org
AGGLUTININS, ANIMAL CELLS, ANIMALS, BIOLOGICAL EFFECTS, BIOLOGICAL
MATERIALS, BLOOD, BLOOD CELLS, BODY FLUIDS, CONNECTIVE TISSUE CELLS, …
MATERIALS, BLOOD, BLOOD CELLS, BODY FLUIDS, CONNECTIVE TISSUE CELLS, …
[CITATION][C] Effects of irradiation on senescence accelerated mouse (SAM)
M Iseki, M Kishikawa, M Sakae - Nagasaki Igakkai Zasshi, 1992 - inis.iaea.org
[CITATION][C] Morphometric study of lipofuscin in SAMP8/TaNgs Purkinje neurons. Relationship between radiation and acceleration of aging
M Iseki, M Kishikawa, H Kondo, M Sakae, I Sekine… - Hiroshima Igaku, 1996 - inis.iaea.org