Host genetics and the gut microbiome can both influence metabolic phenotypes. However,
whether host genetic variation shapes the gut microbiome and interacts with it to affect host …

Studies in mice and humans have revealed intriguing associations between host genetics
and the microbiome. Here we report a 16S rRNA-based analysis of the gut microbiome in …

Background Variation in the human fecal microbiota has previously been associated with
body mass index (BMI). Although obesity is a global health burden, the accumulation of …

Background Frailty is arguably the biggest problem associated with population ageing, and
associates with gut microbiome composition in elderly and care-dependent individuals. Here …

Introduction Several circulating metabolites derived from bacterial protein fermentation have
been found to be inversely associated with renal function but the timing and disease …

The preservation of cognitive abilities with aging is a priority both for individuals and nations
given the aging populations of many countries. Recently the gut microbiome has been …

Obesity and its associated diseases are one of the major causes of death worldwide. The
gut microbiota has been identified to have essential regulatory effects on human metabolism …

Objective Abdominal obesity is associated with increased risk of type 2 diabetes (T2D) and
cardiovascular disease. The aim of this study was to assess whether metabolomic markers of …

The pathogenesis of autoimmune thyroid diseases (AITD) is poorly understood and the
association between different immune features and the germline variants involved in AITD are …

… Catherine Beaumont, discovering that her own daughter had suffered ritual abuse, found
herself angry with God, unable to accept comfort, and confronted with the awful truth that she …