User profiles for Makrina Totsika
 | Makrina Totsika MSc PhDVice-Chancellor's Senior Research Fellow, Group Leader in Infection and Immunity Program Verified email at qut.edu.au Cited by 8619 |
Global dissemination of a multidrug resistant Escherichia coli clone
Escherichia coli sequence type 131 (ST131) is a globally disseminated, multidrug resistant (MDR)
clone responsible for a high proportion of urinary tract and bloodstream infections. …
clone responsible for a high proportion of urinary tract and bloodstream infections. …
Bacterial biofilm eradication agents: a current review
Most free-living bacteria can attach to surfaces and aggregate to grow into multicellular
communities encased in extracellular polymeric substances called biofilms. Biofilms are …
communities encased in extracellular polymeric substances called biofilms. Biofilms are …
Host–pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection
Bladder infections affect millions of people yearly, and recurrent symptomatic infections (cystitis)
are very common. The rapid increase in infections caused by multidrug-resistant …
are very common. The rapid increase in infections caused by multidrug-resistant …
DSB proteins and bacterial pathogenicity
If DNA is the information of life, then proteins are the machines of life — but they must be
assembled and correctly folded to function. A key step in the protein-folding pathway is the …
assembled and correctly folded to function. A key step in the protein-folding pathway is the …
Insights into a Multidrug Resistant Escherichia coli Pathogen of the Globally Disseminated ST131 Lineage: Genome Analysis and Virulence Mechanisms
Escherichia coli strains causing urinary tract infection (UTI) are increasingly recognized as
belonging to specific clones. E. coli clone O25b:H4-ST131 has recently emerged globally as …
belonging to specific clones. E. coli clone O25b:H4-ST131 has recently emerged globally as …
Discovery of an archetypal protein transport system in bacterial outer membranes
Bacteria have mechanisms to export proteins for diverse purposes, including colonization of
hosts and pathogenesis. A small number of archetypal bacterial secretion machines have …
hosts and pathogenesis. A small number of archetypal bacterial secretion machines have …
Uropathogenic Escherichia coli virulence and innate immune responses during urinary tract infection
Urinary tract infections (UTI) are among the most common infectious diseases of humans and
are the most common nosocomial infections in the developed world. It is estimated that 40–…
are the most common nosocomial infections in the developed world. It is estimated that 40–…
Sortase A: an ideal target for anti-virulence drug development
S Cascioferro, M Totsika, D Schillaci - Microbial pathogenesis, 2014 - Elsevier
Sortase A is a membrane enzyme responsible for the anchoring of surface-exposed proteins
to the cell wall envelope of Gram-positive bacteria. As a well-studied member of the sortase …
to the cell wall envelope of Gram-positive bacteria. As a well-studied member of the sortase …
Chaperone-Usher Fimbriae of Escherichia coli
Chaperone-usher (CU) fimbriae are adhesive surface organelles common to many Gram-negative
bacteria. Escherichia coli genomes contain a large variety of characterised and …
bacteria. Escherichia coli genomes contain a large variety of characterised and …
The Serum Resistome of a Globally Disseminated Multidrug Resistant Uropathogenic Escherichia coli Clone
Escherichia coli ST131 is a globally disseminated, multidrug resistant clone responsible for
a high proportion of urinary tract and bloodstream infections. The rapid emergence and …
a high proportion of urinary tract and bloodstream infections. The rapid emergence and …
