Boundary cap (BC) cells are neural crest derivatives that form clusters at the surface of the
neural tube, at entry and exit points of peripheral nerve roots. Using various knock-in alleles of …

Background: We previously reported that N-(4-hydroxyphenyl)retinamide (4-HPR, fenretinide)
treatment caused large increases of ceramide levels in neuroblastoma cell lines and …

… Lisa Melton … Protein arrays and protein assays in parallel are enabling researchers to look
at protein interactions and activity on a large scale, as Lisa Melton finds out. … Lisa Melton …

Sanfilippo syndrome is a group of rare, complex, and progressive neurodegenerative
lysosomal storage disorders that is characterized by childhood dementia. The clinical …

The recent unprecedented progress in ageing research and drug discovery brings together
fundamental research and clinical applications to advance the goal of promoting healthy …

Objective Multiple sclerosis is a complex neurological disease which can cause impairment
in a range of aspects of an individual's life. It often requires a degree of adjustment and peer …

Several neurodegenerative disorders, including Alzheimer's and Parkinson's diseases, are
associated with immunocompetent microglia, leading to the suggestion that chronic glial‐…

Therapies for infiltrative inflammation in multiple sclerosis (MS) have advanced greatly, but
neurodegeneration and compartmentalized inflammation remain virtually untargeted as in …

MOLECULAR MEDICINE TODAY, NOVEMBER 1999 (VOL. 5) the expressed sequence tag (EST)
databases pioneered by DNA sequencers to help them to locate genes. The database-…

You name it, if it's an antioxidant, we'll swallow it by the bucket-load. According to some
estimates around half the adults in the US take antioxidant pills daily in the belief they promote …