Epigenetic silencing including histone modifications and DNA methylation is an important
tumorigenic mechanism 1 . However, its role in cancer immunopathology and immunotherapy …

Hydrogen (H 2 ) production is a latent feasibility of renewable clean energy. The industrial H
2 production is obtained from reforming of natural gas, which consumes a large amount of …

The energy decomposition analysis (EDA) is a powerful method for a quantitative interpretation
of chemical bonds in terms of three major components. The instantaneous interaction …

Aerobic glycolysis regulates T cell function. However, whether and how primary cancer
alters T cell glycolytic metabolism and affects tumor immunity in cancer patients remains a …

Live regulatory T cells (T reg cells) suppress antitumor immunity, but how T reg cells behave
in the metabolically abnormal tumor microenvironment remains unknown. Here we show …

Programmed death-1 ligand (PD-L1, B7-H1) and programmed cell death protein 1 (PD-1)
pathway blockade is a promising therapy for treating cancer. However, the mechanistic …

Importance In adults undergoing hip fracture surgery, regional anesthesia may reduce
postoperative delirium, but there is uncertainty about its effectiveness. Objective To investigate, in …

Myeloid-derived suppressor cells (MDSCs) and cancer stem cells (CSCs) are important
cellular components in the cancer microenvironment and may affect cancer phenotype and …

Growth of silver nanoparticles by the citrate reduction of silver nitrate under the range of pH
from 5.7 to 11.1 was investigated systematically and quantitatively. Reduction of the silver …

Effector T cells and fibroblasts are major components in the tumor microenvironment. The
means through which these cellular interactions affect chemoresistance is unclear. Here, we …