Systemic inflammation markers have been linked to increased cancer risk and mortality in a
number of studies. However, few studies have estimated pre-diagnostic associations of …

Background Malignant Pleural Mesothelioma (MPM) is an aggressive disease related to
asbestos exposure, with no effective therapeutic options. Methods We undertook unsupervised …

Background The National Health Service England (NHS) classifies individuals as eligible for
lung cancer screening using two risk prediction models, PLCOm2012 and Liverpool Lung …

Background Lung cancer risk prediction models might efficiently identify individuals who
should be offered lung cancer screening. However, their performance has not been …

Background We sought to develop a proteomics-based risk model for lung cancer and
evaluate its risk-discriminatory performance in comparison with a smoking-based risk model (…

Background The relation between blood pressure and kidney cancer risk is well established
but complex and different study designs have reported discrepant findings on the relative …

The Integrative Analysis of Lung Cancer Etiology and Risk (INTEGRAL) program is an NCI-funded
initiative with an objective to develop tools to optimize low-dose CT (LDCT) lung …

Background Opium consumption has recently been identified as a carcinogen, but the impact
of opium use on cancer burden is unknown. We aimed to evaluate the fraction of cancers …

Background: We evaluated the temporal association between kidney function, assessed by
estimated glomerular filtration rate (eGFR), and the risk of incident renal cell carcinoma (RCC…

Cell‐mediated immune suppression may play an important role in lung carcinogenesis. We
investigated the associations for circulating levels of tryptophan, kynurenine, kynurenine:…