[HTML][HTML] Diet-induced obese mice have increased mortality and altered immune responses when infected with influenza virus

AG Smith, PA Sheridan, JB Harp, MA Beck - The Journal of nutrition, 2007 - Elsevier
Obesity is associated with an impaired immune response, an increased susceptibility to
bacterial infection, and a chronic increase in proinflammatory cytokines such as IL-6 and TNFα. …

Differential effects of flavonoids on 3T3-L1 adipogenesis and lipolysis

AW Harmon, JB Harp - American Journal of Physiology-cell …, 2001 - journals.physiology.org
Flavonoids, polyphenolic compounds that exist widely in plants, inhibit cell proliferation and
increase cell differentiation in many cancerous and noncancerous cell lines. Because …

[HTML][HTML] Why do obese patients not lose more weight when treated with low-calorie diets? A mechanistic perspective

SB Heymsfield, JB Harp, ML Reitman… - The American journal of …, 2007 - Elsevier
Maximal weight loss observed in low-calorie diet (LCD) studies tends to be small, and the
mechanisms leading to this low treatment efficacy have not been clarified. Less-than-expected …

[PDF][PDF] Effect of olanzapine on body composition and energy expenditure in adults with first-episode psychosis

…, RC Barrier Jr, JA Lieberman, JB Harp - American Journal of …, 2005 - psychiatryonline.org
OBJECTIVE: Weight gain is a commonly observed adverse effect of atypical antipsychotic
medications, but associated changes in energy balance and body composition are not well …

Obesity in the national football league

JB Harp, L Hecht - Jama, 2005 - jamanetwork.com
Methods Methods Weights, heights, and positions for active NFL football players in the 2003-2004
season were obtained from the official NFL Web site. 4 The Carolina Panthers …

Role of Janus kinase/signal transducer and activator of transcription and mitogen-activated protein kinase cascades in angiotensin II-and platelet-derived growth …

MB Marrero, B Schieffer, B Li, J Sun, JB Harp… - Journal of Biological …, 1997 - jbc.org
In vascular smooth muscle cells, the induction of early growth response genes involves the
Janus kinase (JAK)/signal transducer and activators of transcription (STAT) and the Ras/Raf-1…

Genistein inhibits CCAAT/enhancer-binding protein β (C/EBPβ) activity and 3T3-L1 adipogenesis by increasing C/EBP homologous protein expression

AW Harmon, YM Patel, JB Harp - Biochemical Journal, 2002 - portlandpress.com
The tyrosine kinase inhibitor genistein inhibits 3T3-L1 adipogenesis when present during
the first 72h of differentiation. In this report, we investigated the underlying mechanisms …

[HTML][HTML] Increased energy expenditure, dietary fat wasting, and resistance to diet-induced obesity in mice lacking renin

…, CH Wang, RR Bowers, TJ Bartness, HS Kim, JB Harp - Cell metabolism, 2007 - cell.com
An overactive renin-angiotensin system is associated with obesity and the metabolic
syndrome. However, the mechanisms behind it are unclear. Cleaving angiotensinogen to …

Adipose-specific disruption of signal transducer and activator of transcription 3 increases body weight and adiposity

…, J Deng, MC Bond, TP Combs, JB Harp - …, 2008 - academic.oup.com
… *Address all correspondence and requests for reprints to: Joyce B. Harp, MD, Department
of Nutrition, CB 7461 McGavran Greenberg Hall, University of North Carolina at Chapel Hill, …

Double-blind, placebo-controlled investigation of amantadine for weight loss in subjects who gained weight with olanzapine

…, H Gu, JA Lieberman, JB Harp… - American Journal of …, 2005 - psychiatryonline.org
OBJECTIVE: This study sought to determine if amantadine affects weight gain in psychiatric
patients taking olanzapine. METHOD: Twenty-one adults who had gained at least 5 lb with …