▪ Abstract The development and function of T lymphocytes are regulated tightly by signal
transduction pathways that include specific cell-surface receptors, intracellular signaling …

Mature single-positive (SP) T lymphocytes enter a “resting” state in which they are proliferatively
quiescent and relatively resistant to apoptosis. The molecular mechanisms regulating …

Eukaryotic cells respond to unfolded proteins in their endoplasmic reticulum (ER stress), amino
acid starvation, or oxidants by phosphorylating the α subunit of translation initiation factor …

THE zinc-finger transcription factor GATA-3 is expressed in haematopoietic cells and in the
developing kidney and nervous system 1–7 . Within the haematopoietic lineages, expression …

The transcriptional programs that regulate blood vessel formation are largely unknown. In
this paper, we examine the role of the zinc finger transcription factor LKLF in murine blood …

Previous studies have suggested that the GATA4 transcription factor plays an important role
in regulating mammalian cardiac development. In the studies described in this report we …

The use of replication–defective adenoviruses (RDAd) for human gene therapy has been
limited by host immune responses that result in transient recombinant gene expression in vivo. …

CD28 is a 44-kDa glycoprotein expressed as a homodimer on the surface of a major subset
of human T cells. Previous studies have demonstrated that the binding of monoclonal …

THE Ets-1 proto-oncogene 1 is a member of the Ets family of eukaryotic transcription factors
2á¤-7 . Members of this family play important roles in regulating gene expression in …

Genes that control the early stages of adipogenesis remain largely unknown. Here, we show
that murine GATA-2 and GATA-3 are specifically expressed in white adipocyte precursors …