The long-term stability of the human gut microbiota
JJ Faith, JL Guruge, M Charbonneau, S Subramanian… - Science, 2013 - science.org
Background Understanding the dynamics and stability of the human gut microbiota is
important if its characterization is to play a role in the diagnosis, treatment, and prevention of …
important if its characterization is to play a role in the diagnosis, treatment, and prevention of …
Epithelial attachment alters the outcome of Helicobacter pylori infection
JL Guruge, PG Falk, RG Lorenz, M Dans… - Proceedings of the …, 1998 - pnas.org
Genetically defined in vivo models are needed to assess the importance of target cell
attachment in bacterial pathogenesis. Gastric colonization by Helicobacter pylori in human …
attachment in bacterial pathogenesis. Gastric colonization by Helicobacter pylori in human …
IgA response to symbiotic bacteria as a mediator of gut homeostasis
DA Peterson, NP McNulty, JL Guruge, JI Gordon - Cell host & microbe, 2007 - cell.com
Colonization of germ-free mice with a normal gut microbiota elicits bacteria-specific IgA
antibody responses. The effects of these responses on microbial and host biology remain poorly …
antibody responses. The effects of these responses on microbial and host biology remain poorly …
Bifidobacterium infantis treatment promotes weight gain in Bangladeshi infants with severe acute malnutrition
…, S Nakshatri, CA Cowardin, JL Guruge… - Science Translational …, 2022 - science.org
Disrupted development of the gut microbiota is a contributing cause of childhood malnutrition.
Bifidobacterium longum subspecies infantis is a prominent early colonizer of the infant gut …
Bifidobacterium longum subspecies infantis is a prominent early colonizer of the infant gut …
Pan-genome of the dominant human gut-associated archaeon, Methanobrevibacter smithii, studied in twins
The human gut microbiota harbors three main groups of H 2 -consuming microbes: methanogens
including the dominant archaeon, Methanobrevibacter smithii, a polyphyletic group of …
including the dominant archaeon, Methanobrevibacter smithii, a polyphyletic group of …
Inducible CRISPR-targeted “knockdown” of human gut Bacteroides in gnotobiotic mice discloses glycan utilization strategies
…, DA Wesener, TR Seebeck, JL Guruge… - Proceedings of the …, 2023 - pnas.org
Understanding how members of the human gut microbiota prioritize nutrient resources is
one component of a larger effort to decipher the mechanisms defining microbial community …
one component of a larger effort to decipher the mechanisms defining microbial community …
Mechanisms by which sialylated milk oligosaccharides impact bone biology in a gnotobiotic mouse model of infant undernutrition
…, VL Kung, MC Hibberd, J Cheng, JL Guruge… - Proceedings of the …, 2019 - pnas.org
Undernutrition in children is a pressing global health problem, manifested in part by impaired
linear growth (stunting). Current nutritional interventions have been largely ineffective in …
linear growth (stunting). Current nutritional interventions have been largely ineffective in …
Combined prebiotic and microbial intervention improves oral cholera vaccination responses in a mouse model of childhood undernutrition
…, PP Ahern, NW Griffin, J Cheng, JL Guruge… - Cell host & …, 2020 - cell.com
Undernourished children in low-income countries often exhibit poor responses to oral
vaccination. Perturbed microbiota development is linked to undernutrition, but whether and how …
vaccination. Perturbed microbiota development is linked to undernutrition, but whether and how …
[HTML][HTML] Characterizing the interactions between a naturally primed immunoglobulin A and its conserved Bacteroides thetaiotaomicron species-specific epitope in …
DA Peterson, JD Planer, JL Guruge, L Xue… - Journal of Biological …, 2015 - Elsevier
The adaptive immune response to the human gut microbiota consists of a complex repertoire
of antibodies interacting with a broad range of taxa. Fusing intestinal lamina propria …
of antibodies interacting with a broad range of taxa. Fusing intestinal lamina propria …
Strain-level functional variation in the human gut microbiota based on bacterial binding to artificial food particles
ML Patnode, JL Guruge, JJ Castillo, GA Couture… - Cell host & …, 2021 - cell.com
Greater understanding of the spatial relationships between members of the human gut
microbiota and available nutrients is needed to gain deeper insights about community dynamics …
microbiota and available nutrients is needed to gain deeper insights about community dynamics …