The serpins are an expanding superfamily of structurally similar but functionally diverse proteins

…, E Remold-O'Donnell, GS Salvesen, J Travis… - Journal of Biological …, 2001 - jbc.org
The serpins (serine proteinase inhibitors) are a superfamily of proteins (350–500 amino
acids in size) that fold into a conserved structure and employ a unique suicide substrate-like …

Structure, function, and control of neutrophil proteinases

J Travis - The American journal of medicine, 1988 - Elsevier
Elastase and cathepsin G are two of the major enzymes present in and secreted by human
neutrophils. These proteinases can rapidly degrade connective tissue proteins. However, …

Purification, Characterization, and Sequence Analysis of a Potential Virulence Factor from Porphyromonas gingivalis, Peptidylarginine Deiminase

…, J Potempa, D Farley, J Travis - Infection and immunity, 1999 - journals.asm.org
The initiation and progression of adult-onset periodontitis has been associated with infection
of the gingival sulcus byPorphyromonas gingivalis. This organism utilizes a multitude of …

α1-Antitrypsin and the serpins: variation and countervariation

R Carrell, J Travis - Trends in Biochemical Sciences, 1985 - cell.com
… Robin Carrell and James Travis … described in TIBS (James, 1980). How- … and van der
Zeijst, BAM (1981) church Hospital, New Zealand and James Travis single substitution at the …

[HTML][HTML] Lysine-and arginine-specific proteinases from Porphyromonas gingivalis. Isolation, characterization, and evidence for the existence of complexes with …

R Pike, W McGraw, J Potempa, J Travis - Journal of Biological Chemistry, 1994 - Elsevier
Porphyromonas gingivalis contains many virulence factors that have been implicated as
participants in the progression of periodontal disease. It has been shown to produce …

Gingipains, the major cysteine proteinases and virulence factors of Porphyromonas gingivalis: structure, function and assembly of multidomain protein complexes

…, A Sroka, T Imamura, J Travis - Current Protein and …, 2003 - ingentaconnect.com
Gingipains, extracellular cysteine proteinases of Porphyromonas gingivalis, constitute the
major virulence factor of this periodontopathogenic bacterium. They are the product of three …

Isolation of albumin from whole human plasma and fractionation of albumin-depleted plasma

J Travis, J Bowen, D Tewksbury, D Johnson… - Biochemical …, 1976 - portlandpress.com
The dye Cibacron Blue F-3-GA was conjugated to Sepharose to provide an affinity column
for serum albumin. Passage of whole human plasma through a column of Cibacron Blue-…

New Method for Typing Staphylococcus aureus Strains: Multiple-Locus Variable-Number Tandem Repeat Analysis of Polymorphism and Genetic Relationships of …

…, K Kosowska, W Hryniewicz, J Travis… - Journal of clinical …, 2003 - journals.asm.org
The PCR-based methodology applied to multiple-locus variable numbers of tandem repeat (VNTR)
analysis was recently shown to be a useful technique for the molecular typing of …

The multiple forms of trypsin-like activity present in various strains of Porphyromonas gingivalis are due to the presence of either Arg-gingipain or Lys-gingipain

J Potempa, R Pike, J Travis - Infection and immunity, 1995 - journals.asm.org
Porphyromonas gingivalis contains high concentrations of numerous cysteine proteinases
with trypsin-like activity which have been implicated as important virulence factors in adult-…

Activation of protease-activated receptors by gingipains fromPorphyromonas gingivalis leads to platelet aggregation: a new trait in microbial pathogenicity

…, YP Yuan, AL Jenkins, J Travis… - Blood, The Journal …, 2001 - ashpublications.org
The bacterium Porphyromonas gingivalis is a major etiologic agent in the pathogenesis of
adult periodontitis in humans. Cysteine proteinases produced by this pathogen, termed …