Chemotherapy-induced peripheral neuropathy (CIPN) is a severe and painful adverse
reaction of cancer treatment in patients that is little understood or treated. Cytotoxic drugs that …

Multiple sclerosis (MS) is a chronic neurodegenerative and autoimmune disease. Motor,
sensory and cognitive deficits in MS are commonly accompanied by psychiatric disorders. …

Despite intense investigation, the mechanisms of the different forms of trigeminal neuropathic
pain remain substantially unidentified. The transient receptor potential ankyrin 1 channel (…

Acute gout attacks produce severe joint pain and inflammation associated with monosodium
urate (MSU) crystals leading to oxidative stress production. The transient potential receptor …

It is known that transient receptor potential ankyrin 1 (TRPA1) channels, expressed by
nociceptors, contribute to neuropathic pain. Here we show that TRPA1 is also expressed in …

Migraine remains an elusive and poorly understood disease. The uncertainty is reflected by
the currently unsatisfactory acute and prophylactic treatments for this disease. Genetic and …

Acetaminophen [N‐acetyl‐p‐aminophenol (APAP)] is the most common antipyretic/analgesic
medicine worldwide. If APAP is overdosed, its metabolite, N‐acetyl‐p‐benzo‐…

Although feverfew has been used for centuries to treat pain and headaches and is
recommended for migraine treatment, the mechanism for its protective action remains unknown. …

The transient potential vanilloid 1 receptor (TRPV1) is a calcium-permeable channel responsible
for the transduction and modulation of acute and chronic pain signaling. As such, this …

A presente tese constitui uma análise sociológica da participação de crianças e jovens em
contextos públicos de codecisão, mobilizada a partir das discussões atuais sobre a …