Docosahexaenoic acid (DHA, 22: 6n-3) and arachidonic acid (AA, 20: 4n-6) are the major
polyunsaturated fatty acids in the membranes of brain and retinal cells. Animals specifically …

Several studies suggest that (n-3) PUFA may play a role in the regulation of cognitive functions,
locomotor and exploratory activity, and affective disorders. Additionally, (n-3) PUFA affect …

Brain cells are especially rich in polyunsaturated fatty acids (PUFA), mainly the n-3 PUFA
docosahexaenoic acid (DHA) and the n-6 PUFA arachidonic acid (AA). They are released from …

Chronic stress causes the release of glucocorticoids, which greatly influence cerebral
function, especially glutamatergic transmission. These stress-induced changes in …

This study aims to determine whether the regulation of extracellular glutamate is altered during
aging and its possible consequences on synaptic transmission and plasticity. A decrease …

Omega-3 fatty acids are important for several neuronal and cognitive functions. Altered omega-3
fatty acid status has been implicated in reduced resistance to stress and mood disorders…

Epidemiological data suggest that a poor ω3 status favoured by the low ω3/ω6 polyunsaturated
fatty acids ratio in western diets contributes to cognitive decline in the elderly, but …

Although it is agreed that n‐3 polyunsaturated fatty acids (PUFAs) are important for brain
function, it has yet to be demonstrated how they are involved in precise cellular mechanisms. …

Docosahexaenoic acid (DHA), the main n‐3 polyunsaturated fatty acid (PUFA) in membranes,
is particularly abundant in brain cells. Decreased cerebral concentrations of DHA, …

The many functions of astrocytes, such as glutamate recycling and morphological plasticity,
enable them to stabilize synapses environment and protect neurons. Little is known about …