User profiles for G. Travis Tabor
 | G. Travis TaborWashington University School of Medicine in St Louis Verified email at wustl.edu Cited by 414 |
Microglial REV-ERBα regulates inflammation and lipid droplet formation to drive tauopathy in male mice
Alzheimer’s disease, the most common age-related neurodegenerative disease, is characterized
by tau aggregation and associated with disrupted circadian rhythms and dampened …
by tau aggregation and associated with disrupted circadian rhythms and dampened …
Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist
Apolipoprotein E (APOE) is a strong genetic risk factor for late-onset Alzheimer's disease (LOAD).
APOE4 increases and APOE2 decreases risk relative to APOE3. In the P301S mouse …
APOE4 increases and APOE2 decreases risk relative to APOE3. In the P301S mouse …
APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread
A recent case report described an individual who was a homozygous carrier of the APOE3
Christchurch (APOE3ch) mutation and resistant to autosomal dominant Alzheimer's Disease (…
Christchurch (APOE3ch) mutation and resistant to autosomal dominant Alzheimer's Disease (…
TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma
Triggering receptor expressed on myeloid cells 2 (TREM2) plays important roles in brain
microglial function in neurodegenerative diseases, but the role of TREM2 in the GBM TME has …
microglial function in neurodegenerative diseases, but the role of TREM2 in the GBM TME has …
Lack of hepatic apoE does not influence early Aβ deposition: observations from a new APOE knock-in model
Background The apolipoprotein E (APOE) gene is the strongest genetic risk factor for late-onset
Alzheimer disease (AD). ApoE is produced by both astrocytes and microglia in the brain, …
Alzheimer disease (AD). ApoE is produced by both astrocytes and microglia in the brain, …
Current status of amyloid-targeting immunotherapies for Alzheimer's disease
GT Tabor, DM Holtzman - Science translational medicine, 2023 - science.org
… TravisáTabor … In 2021, aducanumab, a recombinant human immunoglobulin G
monoclonal antibody, received Accelerated Approval for the treatment of AD by the US …
monoclonal antibody, received Accelerated Approval for the treatment of AD by the US …
Activity-dependent isomerization of Kv4. 2 by Pin1 regulates cognitive flexibility
Voltage-gated K + channels function in macromolecular complexes with accessory subunits
to regulate brain function. Here, we describe a peptidyl-prolyl cis-trans isomerase NIMA-…
to regulate brain function. Here, we describe a peptidyl-prolyl cis-trans isomerase NIMA-…
Disruption of GpI mGluR-dependent Cav2. 3 translation in a mouse model of fragile X syndrome
Fragile X syndrome (FXS) is an inherited intellectual impairment that results from the loss of
fragile X mental retardation protein (FMRP), an mRNA binding protein that regulates mRNA …
fragile X mental retardation protein (FMRP), an mRNA binding protein that regulates mRNA …
[PDF][PDF] Exploring Possible Roles of Organic Anion-transporting Polypeptides in Invadopodia Function
GT Tabor - 2016 - core.ac.uk
… Finally, thanks to my mom, Martha Brophy, and my brother, Trent Tabor, who have helped
me through the rough spots. Everything I do is in memory of my father, George Roley Tabor, …
me through the rough spots. Everything I do is in memory of my father, George Roley Tabor, …
IMMU-28. Trem2 inhibition reprograms myeloid cells to stimulate anti-tumor immunity through both direct and indirect mechanisms
Oncolytic virotherapy holds great potential to treat high-grade gliomas by harnessing virus-mediated
oncolysis to stimulate anti-tumor immune responses. However, the efficacy of …
oncolysis to stimulate anti-tumor immune responses. However, the efficacy of …