The development of the microbiome from infancy to childhood is dependent on a range of
factors, with microbial–immune crosstalk during this time thought to be involved in the …

Laboratory mice, while paramount for understanding basic biological phenomena, are limited
in modeling complex diseases of humans and other free-living mammals. Because the …

There is mounting evidence that the microbiome has potent immunoregulatory functions.
We assessed the effects of intestinal dysbiosis in a model of Sjögren syndrome (SS) by …

Purpose: Usage of different types of contact lenses is associated with increased risk of sight-threatening
complications. Changes in the ocular microbiome caused by contact lens wear …

Multiple studies have identified changes within the gut microbiome in response to diarrheal-inducing
bacterial pathogens. However, examination of the microbiome in response to viral …

The oral microbiome has been linked to a number of chronic inflammatory conditions, including
obesity, diabetes, periodontitis, and cancers of the stomach and liver. These conditions …

Objectives To characterize the microbial environment of workers in academic mouse
research facilities using endotoxin, 16S qPCR, and 16S amplicon sequencing. To determine …

Background: Previously rare A2ML1 variants were identified to confer otitis media susceptibility
in an indigenous Filipino community and in otitis-prone US children. The goal of this …

… Ajami, data analysis and interpretation, manuscript writing, final approval, accountable for
all aspects of the work; Diane S. Hutchinson, data analysis and interpretation, manuscript …

Mouse models are paramount for understanding basic immunological mechanisms, but can
be limited in recapitulating human diseases. The microbiome has been identified as a main …