User profiles for David W Provance-Jr

D. William Provance, Jr.

Oswaldo Cruz Foundation/Fiocruz
Verified email at cdts.fiocruz.br
Cited by 4098

[HTML][HTML] SARS-CoV-2 proteins bind to hemoglobin and its metabolites

…, CR Alves, MCS Pereira, DW Provance Jr… - International journal of …, 2021 - mdpi.com
(1) Background: coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has been linked to hematological dysfunctions, but …

[HTML][HTML] An Update on the Therapeutic Potential of Antimicrobial Peptides against Acinetobacter baumannii Infections

K Rangel, GC Lechuga, DW Provance Jr, CM Morel… - Pharmaceuticals, 2023 - mdpi.com
The rise in antibiotic-resistant strains of clinically important pathogens is a major threat to
global health. The World Health Organization (WHO) has recognized the urgent need to …

[HTML][HTML] Enhanced assessment of cross-reactive antigenic determinants within the Spike protein

…, DC Bou-Habib, CM Morel, DW Provance Jr… - International journal of …, 2024 - mdpi.com
Despite successful vaccination efforts, the emergence of new SARS-CoV-2 variants poses
ongoing challenges to control COVID-19. Understanding humoral responses regarding SARS…

[HTML][HTML] Metabolic Alteration of Trypanosoma cruzi during Differentiation of Epimastigote to Trypomastigote Forms

…, PS Gonçalves, GC Lechuga, DW Provance Jr - Pathogens, 2022 - mdpi.com
Intracellular parasites such as Trypanosoma cruzi need to acquire valuable carbon sources
from the host cell to replicate. Here, we investigated the energetic metabolism of T. cruzi …

Performance assessment of a multi-epitope chimeric antigen for the serological diagnosis of acute Mayaro fever

…, AM Durans, LR Gomes, CM Morel, DW Provance Jr… - Scientific Reports, 2021 - nature.com
Mayaro virus (MAYV), which causes mayaro fever, is endemic to limited regions of South
America that may expand due to the possible involvement of Aedes spp. mosquitoes in its …

High-throughput IgG epitope mapping of tetanus neurotoxin: Implications for immunotherapy and vaccine design

…, LR Gomes, SV Cardozo, CM Morel, DW Provance Jr… - Toxins, 2023 - mdpi.com
Tetanus is an acute, fatal disease caused by exotoxins released from Clostridium tetani
during infections. A protective humoral immune response can be induced by vaccinations with …

[HTML][HTML] Chagas Disease Diagnosis with Trypanosoma cruzi-Exclusive Epitopes in GFP

…, ACV Junqueira, SG De-Simone, DW Provance Jr - Vaccines, 2024 - mdpi.com
Serological tests are critical tools in the fight against infectious disease. They detect
antibodies produced during an adaptive immune response against a pathogen with an …

[HTML][HTML] Mapping IgA epitope and cross-reactivity between Severe acute Respiratory Syndrome-Associated Coronavirus 2 and DENV

…, ME Monteiro, CM Morel, DW Provance Jr - Vaccines, 2023 - mdpi.com
Background: The newly introduced COVID-19 vaccines have reduced disease severity and
hospitalizations. However, they do not significantly prevent infection or transmission. In the …

[HTML][HTML] Trypanosoma cruzi Presenilin-Like Transmembrane Aspartyl Protease: Characterization and Cellular Localization

…, CCG Bottino, RT Pinho, DW Provance-Jr… - Biomolecules, 2020 - mdpi.com
The increasing detection of infections of Trypanosoma cruzi, the etiological agent of Chagas
disease, in non-endemic regions beyond Latin America has risen to be a major public …

B-Cell Epitope Mapping of the Vibrio cholera Toxins A, B, and P and an ELISA Assay

…, GC Lechuga, SV Cardoso, DW Provance Jr… - International Journal of …, 2022 - mdpi.com
Oral immunization with the choleric toxin (CT) elicits a high level of protection against its
enterotoxin activities and can control cholera in endemic settings. However, the complete B-cell …