We report a comprehensive analysis of 412 muscle-invasive bladder cancers characterized
by multiple TCGA analytical platforms. Fifty-eight genes were significantly mutated, and the …

To explore the biology of lung adenocarcinoma (LUAD) and identify new therapeutic
opportunities, we performed comprehensive proteogenomic characterization of 110 tumors and …

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor patient
survival. Toward understanding the underlying molecular alterations that drive PDAC …

To elucidate the deregulated functional modules that drive clear cell renal cell carcinoma (ccRCC),
we performed comprehensive genomic, epigenomic, transcriptomic, proteomic, and …

Glioblastoma (GBM) is the most aggressive nervous system cancer. Understanding its
molecular pathogenesis is crucial to improving diagnosis and treatment. Integrated analysis of …

Lung squamous cell carcinoma (LSCC) remains a leading cause of cancer death with few
therapeutic options. We characterized the proteogenomic landscape of LSCC, providing a …

We studied 137 primary testicular germ cell tumors (TGCTs) using high-dimensional assays
of genomic, epigenomic, transcriptomic, and proteomic features. These tumors exhibited …

We undertook a comprehensive proteogenomic characterization of 95 prospectively collected
endometrial carcinomas, comprising 83 endometrioid and 12 serous tumors. This analysis …

Clear cell renal cell carcinomas (ccRCCs) represent ∼75% of RCC cases and account for
most RCC-associated deaths. Inter- and intratumoral heterogeneity (ITH) results in varying …

We characterized a prospective endometrial carcinoma (EC) cohort containing 138 tumors
and 20 enriched normal tissues using 10 different omics platforms. Targeted quantitation of …