Activation of the transcription factor nuclear factor kappa B (NF-κB) is controlled by sequential
phosphorylation, ubiquitination, and degradation of its inhibitory subunit IκB. A large …

Activation of the transcription factor NF-κB is controlled by the sequential phosphorylation,
ubiquitination, and degradation of its inhibitory subunit, IκB. We recently purified a large …

CBF1 is a member of the CSL family of DNA binding factors, which mediate either
transcriptional repression or transcriptional activation. CSL proteins play a central role in Notch …

DNA-binding transcriptional regulators interpret the genome's regulatory code by binding to
specific sequences to induce or repress gene expression 1 . Comparative genomics has …

… Young goes on to consider questionings of the limits of Western knowledge in the work of
Edward Said, Gayatri Chakravorty Spivak and Homi Bhabha. For Young, … JC Young returns to …

The clinical benefit of the human immunodeficiency virus type 1 (HIV-1) nonnucleoside
reverse transcriptase (RT) inhibitors (NNRTIs) is limited by the rapid selection of inhibitor-…

This volume appears almost exactly a decade after the commitment was made to undertake
the study, in late 1965. With such an elephantine gestation period, the work has …

Although dramatic amphibian population declines have been reported worldwide, our
understanding of the extent of the declines in Latin America, where amphibian diversity is high, is …

… B, and B~ are the reduced bulk moduli from the … Beyond the first zero in B(x), corresponding
to g(x) =1, the magnitude of B… B, and B~ are the reduced bulk moduli from the compressibility …

… For mothers of young children and young adolescents in particular, managing their child's
co-operation with treatment, including taking medicines, physical examinations, unpleasant …