User profiles for Caroline Dean

Caroline Dean

Royal Society Professor, John Innes Centre, Norwich
Verified email at jic.ac.uk
Cited by 47544

Cold-induced silencing by long antisense transcripts of an Arabidopsis Polycomb target

S Swiezewski, F Liu, A Magusin, C Dean - Nature, 2009 - nature.com
Transcription in eukaryotic genomes generates an extensive array of non-protein-coding
RNA, the functional significance of which is mostly unknown 1 . We are investigating the link …

Long non-coding RNAs: definitions, functions, challenges and recommendations

…, HY Chang, LL Chen, R Chen, C Dean… - … reviews Molecular cell …, 2023 - nature.com
Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes
of complex organisms. The term ‘lncRNAs’ encompasses RNA polymerase I (Pol I), Pol II …

Molecular Analysis of FRIGIDA, a Major Determinant of Natural Variation in Arabidopsis Flowering Time

…, J West, C Lister, S Michaels, R Amasino, C Dean - Science, 2000 - science.org
Vernalization, the acceleration of flowering by a long period of cold temperature, ensures that
many plants overwinter vegetatively and flower in spring. In Arabidopsis, allelic variation at …

Vernalization requires epigenetic silencing of FLC by histone methylation

…, C Lister, Z Lippman, RA Martienssen, C Dean - Nature, 2004 - nature.com
To ensure flowering in favourable conditions, many plants flower only after an extended period
of cold, namely winter. In Arabidopsis, the acceleration of flowering by prolonged cold, a …

Multiple pathways in the decision to flower: enabling, promoting, and resetting

PK Boss, RM Bastow, JS Mylne, C Dean - The plant cell, 2004 - academic.oup.com
At a certain point in their life cycle, annual plants undergo a major developmental transition
and switch from vegetative to reproductive development. This process is rarely reversible, …

The VERNALIZATION 2 gene mediates the epigenetic regulation of vernalization in Arabidopsis

AR Gendall, YY Levy, A Wilson, C Dean - Cell, 2001 - cell.com
The acceleration of flowering by a long period of low temperature, vernalization, is an adaptation
that ensures plants overwinter before flowering. Vernalization induces a developmental …

Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines

…, MA Amer, I Baxter, B Brachi, J Chory, C Dean… - Nature, 2010 - nature.com
Although pioneered by human geneticists as a potential solution to the challenging problem
of finding the genetic basis of common human diseases 1 , 2 , genome-wide association (…

Transgenic plants protected from insect attack

…, H Höfte, S Jansens, M De Beuckeleer, C Dean… - Nature, 1987 - nature.com
The Gram-positive bacterium Bacillus thuringiensis produces proteins which are specifically
toxic to a variety of insect species. Modified genes have been derived from bt2, a toxin gene …

Arabidopsis, the Rosetta Stone of Flowering Time?

GG Simpson, C Dean - Science, 2002 - science.org
Multiple environmental and endogenous inputs regulate when plants flower. The molecular
genetic dissection of flowering time control in Arabidopsis has identified an integrated …

Arabidopsis thaliana: A Model Plant for Genome Analysis

DW Meinke, JM Cherry, C Dean, SD Rounsley… - Science, 1998 - science.org
Arabidopsis thaliana is a small plant in the mustard family that has become the model system
of choice for research in plant biology. Significant advances in understanding plant growth …