Therapy development for adult diffuse glioma is hindered by incomplete knowledge of somatic
glioma driving alterations and suboptimal disease classification. We defined the complete …

Background Glioblastoma remains one of the most devastating human malignancies, and
despite therapeutic advances, there are no drugs that significantly improve the patient survival…

Central nervous system synapses have an intrinsic plastic capacity to adapt to new conditions
with rapid changes in their structure. Such activity‐dependent refinement occurs during …

The term “paraclinoid aneurysms”, has been used for aneurysms of the internal carotid artery
(ICA) between the cavernous sinus and the posterior communicating artery. Due to their …

BACKGROUND: Parasagittal meningioma is one that fills the parasagittal angle, with no
brain tissue between the tumor and the SSS. Invasion of the SSS is a challenge for complete …

Metabotropic glutamate receptor type 5 (mGluR5) upregulation in temporal lobe epilepsy (TLE)
and the correlation of its expression with features of hippocampal sclerosis (HS) remains …

This investigation analyzed the immunoexpression of FasL, Fas, cleaved caspase-8, and
cleaved caspase-3 in glioblastomas. Formalin-fixed and paraffin-embedded glioblastoma …

Glioblastoma (GBM) is the most malignant glioma and represents 29% of all brain tumors.
Tumorigenesis is intimately connected with characteristics acquired in the physiologic …

Astrocytomas are the most common primary brain tumors. They are very resistant to therapies
and usually progress rapidly to high-grade lesions. Here, we investigated the potential role …

Background Despite the strong association between epilepsy and psychiatric comorbidities,
few biological substrates are currently described. We have previously reported …