Relapse is a major problem in acute myeloid leukemia (AML) and adversely affects survival.
In this phase 2 study, we investigated the effect of vaccination with dendritic cells (DCs) …

Background Infections remain a leading cause of morbidity and mortality in patients with
reduced immunity caused by haematological disease and chemotherapy‐induced neutropenia. …

SARS-CoV-2 mRNA vaccines induce robust anti-spike (S) antibody and CD4 + T cell
responses. It is not yet clear whether vaccine-induced follicular helper CD4 + T (T FH ) cell …

Background Myeloid cells are an abundant leukocyte in many types of tumors and contribute
to immune evasion. Expression of the enzyme arginase 1 (Arg1) is a defining feature of …

Reconstruction of craniomaxillofacial bone defects using 3D-printed hydroxyapatite (HA)
bioceramic patient-specific implants (PSIs) is a new technique with great potential. This study …

Cancer can involve non-resolving, persistent inflammation where varying numbers of tumor-associated
macrophages (TAMs) infiltrate and adopt different activation states between anti-…

Severe influenza A virus (IAV) infections can result in hyper-inflammation, lung injury and
acute respiratory distress syndrome 1 , 2 , 3 , 4 – 5 (ARDS), for which there are no effective …

Evidence suggests that innate and adaptive cellular responses mediate resistance to the
influenza virus and confer protection after vaccination. However, few studies have resolved the …

Management of fever in prolonged, profound neutropenia remains challenging with many
possible infectious and non-infectious causes. We investigated whether procalcitonin (PCT) is …

SARS-CoV-2 infection causes diverse outcomes ranging from asymptomatic infection to
respiratory distress and death. A major unresolved question is whether prior immunity to …