We describe the landscape of somatic genomic alterations based on multidimensional and
comprehensive characterization of more than 500 glioblastoma tumors (GBMs). We identify …

We describe the landscape of genomic alterations in cutaneous melanomas through DNA,
RNA, and protein-based analysis of 333 primary and/or metastatic melanomas from 331 …

There is substantial heterogeneity among primary prostate cancers, evident in the spectrum
of molecular abnormalities and its variable clinical course. As part of The Cancer Genome …

Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Here, we
describe the genomic landscape of 496 PTCs. We observed a low frequency of somatic …

Therapy development for adult diffuse glioma is hindered by incomplete knowledge of somatic
glioma driving alterations and suboptimal disease classification. We defined the complete …

We describe the landscape of somatic genomic alterations of 66 chromophobe renal cell
carcinomas (ChRCCs) on the basis of multidimensional and comprehensive characterization, …

Adenocarcinoma of the lung is the leading cause of cancer death worldwide. Here we
report molecular profiling of 230 resected lung adenocarcinomas using messenger RNA, …

Molecular alterations involving the PI3K/AKT/mTOR pathway (including mutation, copy
number, protein, or RNA) were examined across 11,219 human cancers representing 32 major …

Previous studies have established that a subset of head and neck tumors contains human
papillomavirus (HPV) sequences and that HPV-driven head and neck cancers display distinct …

Lung cancer is the second most frequently diagnosed cancer and the leading cause of
cancer-related mortality worldwide. Tumour ecosystems feature diverse immune cell types. …