Deep learning with differential privacy
Machine learning techniques based on neural networks are achieving remarkable results in
a wide variety of domains. Often, the training of models requires large, representative …
a wide variety of domains. Often, the training of models requires large, representative …
Genomic classification of cutaneous melanoma
We describe the landscape of genomic alterations in cutaneous melanomas through DNA,
RNA, and protein-based analysis of 333 primary and/or metastatic melanomas from 331 …
RNA, and protein-based analysis of 333 primary and/or metastatic melanomas from 331 …
[HTML][HTML] The molecular taxonomy of primary prostate cancer
…, AD Cherniack, S Chevalier, L Chin, J Cho, A Chu… - Cell, 2015 - cell.com
There is substantial heterogeneity among primary prostate cancers, evident in the spectrum
of molecular abnormalities and its variable clinical course. As part of The Cancer Genome …
of molecular abnormalities and its variable clinical course. As part of The Cancer Genome …
Integrated genomic characterization of papillary thyroid carcinoma
…, AD Cherniack, D Cheung, L Chin, J Cho, A Chu… - Cell, 2014 - cell.com
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Here, we
describe the genomic landscape of 496 PTCs. We observed a low frequency of somatic …
describe the genomic landscape of 496 PTCs. We observed a low frequency of somatic …
[HTML][HTML] Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin
Recent genomic analyses of pathologically defined tumor types identify "within-a-tissue"
disease subtypes. However, the extent to which genomic signatures are shared across tissues …
disease subtypes. However, the extent to which genomic signatures are shared across tissues …
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
Medulloblastoma, the most common malignant paediatric brain tumour, is currently treated
with nonspecific cytotoxic therapies including surgery, whole-brain radiation, and aggressive …
with nonspecific cytotoxic therapies including surgery, whole-brain radiation, and aggressive …
Comprehensive molecular profiling of lung adenocarcinoma
Adenocarcinoma of the lung is the leading cause of cancer death worldwide. Here we
report molecular profiling of 230 resected lung adenocarcinomas using messenger RNA, …
report molecular profiling of 230 resected lung adenocarcinomas using messenger RNA, …
The somatic genomic landscape of chromophobe renal cell carcinoma
We describe the landscape of somatic genomic alterations of 66 chromophobe renal cell
carcinomas (ChRCCs) on the basis of multidimensional and comprehensive characterization, …
carcinomas (ChRCCs) on the basis of multidimensional and comprehensive characterization, …
Integrated genomic characterization of pancreatic ductal adenocarcinoma
…, J Shih, A Ally, M Balasundaram, R Carlsen, A Chu… - Cancer cell, 2017 - cell.com
We performed integrated genomic, transcriptomic, and proteomic profiling of 150 pancreatic
ductal adenocarcinoma (PDAC) specimens, including samples with characteristic low …
ductal adenocarcinoma (PDAC) specimens, including samples with characteristic low …
Large-scale profiling of microRNAs for the cancer genome atlas
A Chu, G Robertson, D Brooks, AJ Mungall… - Nucleic acids …, 2016 - academic.oup.com
The comprehensive multiplatform genomics data generated by The Cancer Genome Atlas (TCGA)
Research Network is an enabling resource for cancer research. It includes an …
Research Network is an enabling resource for cancer research. It includes an …