Background—Ultrasound can cause microbubble destruction. If microbubbles are administered
as a continuous infusion, then their destruction within the myocardium and measurement …

To define the role of capillaries in the control of coronary blood flow (CBF) reserve, we developed
a model of the coronary circulation and evaluated experimental data in its context. Our …

The microvascular rheology and extent of pulmonary retention of second-generation microbubble
ultrasound contrast agents has not previously been well characterized. We assessed …

We postulated that in patients with essential hypertension and normal left ventricular (LV)
systolic function, left atrial (LA) size correlates with LV wall thickness by better reflecting the …

Myocardial contrast echocardiography (MCE) is a new technique for assessing myocardial
perfusion that uses intracoronary injections of microbubbles of air. Because these …

Objectives. We attempted to examine the interactions between ultrasound and microbubbles.
Background. The interactions between microbubbles and ultrasound are poorly understood…

BACKGROUND We hypothesized that myocardial contrast echocardiography (MCE) can be
used to both measure collateral blood flow as well as assess the functional significance of …

Objectives. This study sought to determine the basis of detection of stenosis by myocardial
contrast echocardiography using venous administration of microbubbles and to define the …

BACKGROUND We postulated that the late electrophysiological effects of radiofrequency (RF)
ablation may be related to microvascular injury extending beyond the region of acute …

Vasodilation of microvessels distal to a stenosis results in an increase in myocardial blood
volume (MBV). The purpose of this study was to examine the changes in MBV induced by …