Programming by early nutrition in man

A Lucas - Ciba Foundation Symposium 156‐The Childhood …, 2007 - Wiley Online Library
Whether early diet influences long‐term health or achievement is a key question in nutrition.
Such long‐term consequences would invoke the concept of ‘programming’—a more …

Breast milk and subsequent intelligence quotient in children born preterm

A Lucas, R Morley, TJ Cole, G Lister, C Leeson-Payne - The Lancet, 1992 - Elsevier
There is considerable controversy over whether nutrition in early life has a long-term influence
on neurodevelopment. We have shown previously that, in preterm infants, mother's choice …

An exclusively human milk-based diet is associated with a lower rate of necrotizing enterocolitis than a diet of human milk and bovine milk-based products

…, P Meier, ML Lee, DJ Rechtman, A Lucas - The Journal of …, 2010 - Elsevier
OBJECTIVE: To evaluate the health benefits of an exclusively human milk–based diet compared
with a diet of both human milk and bovine milk–based products in extremely premature …

Early origins of cardiovascular disease: is there a unifying hypothesis?

A Singhal, A Lucas - The Lancet, 2004 - thelancet.com
For personal use. Only reproduce with permission from The Lancet. fed maternal breastmilk.
27 Remarkably, relative undernutrition was beneficial from as early as the first week, 27 …

[HTML][HTML] Programming by early nutrition: an experimental approach

A Lucas - The Journal of nutrition, 1998 - Elsevier
That events during critical or sensitive periods of development may “program” long-term or
life-time structure or function of the organism is well recognized. Evidence for programming by …

Randomised trial of early diet in preterm babies and later intelligence quotient

A Lucas, R Morley, TJ Cole - Bmj, 1998 - bmj.com
Objectives: To determine whether perinatal nutrition influences cognitive function at 7 1/2 - 8
years in children born preterm. Design: Randomised, blinded nutritional intervention trial. …

Early nutrition in preterm infants and later blood pressure: two cohorts after randomised trials

A Singhal, TJ Cole, A Lucas - The Lancet, 2001 - thelancet.com
Background Despite data relating body size in early life to later cardiovascular outcomes,
the hypothesis that nutrition affects such outcomes has not been established. Breastfeeding …

Role of nutritional programming in determining adult morbidity

A Lucas - Archives of disease in childhood, 1994 - pmc.ncbi.nlm.nih.gov
The idea that nutrition during critical windows in early life could influence or'program'long
term development and major disease in adulthood has important biological and public health …

Low nutrient intake and early growth for later insulin resistance in adolescents born preterm

A Singhal, M Fewtrell, TJ Cole, A Lucas - The Lancet, 2003 - thelancet.com
Background In animals, acceleration of neonatal growth is thought to increase the later
propensity to insulin resistance and non-insulin-dependent diabetes, whereas slow growth as a …

How much loss to follow-up is acceptable in long-term randomised trials and prospective studies?

…, M Hadders-Algra, B Koletzko, A Lucas - Archives of disease in …, 2008 - adc.bmj.com
There is increasing evidence that health and development in adult life is influenced or ‘‘programmed’’by
factors, including nutrition, operating during foetal life and infancy. Early …